The analysis found no increased risk of GBS after Pfizer-BioNTech or Moderna (mRNA COVID-19 vaccines). After the first 42 days, the rate of GBS was 11 times higher following J&J/Janssen COVID-19 vaccination. GBS has largely been reported in men ages 50 years and older.īased on a recent analysis of data from the Vaccine Safety Datalink, the rate of GBS within the first 21 days following J&J/Janssen COVID-19 vaccination was found to be 21 times higher than after Pfizer-BioNTech or Moderna (mRNA COVID-19 vaccines). ![]() GBS is a rare disorder where the body’s immune system damages nerve cells, causing muscle weakness and sometimes paralysis. Guillain-Barré Syndrome (GBS) in people who have received the J&J/Janssen COVID-19 vaccine is rare.Updates on Thrombosis with Thrombocytopenia Syndrome (TTS).Case Series of Thrombosis with Thrombocytopenia Syndrome following COVID-19 vaccination-United States, December 2020–August 2021.US Case Reports of Cerebral Venous Sinus Thrombosis With Thrombocytopenia After Vaccination, March 2 to April 21, 2021.CDC scientists have conducted detailed reviews of TTS cases and made the information available to healthcare providers and the public: TTS is a rare but serious adverse event that causes blood clots in large blood vessels and low platelets (blood cells that help form clots).Ī review of reports indicates a causal relationship between the J&J/Janssen COVID-19 vaccine and TTS. Thrombosis with thrombocytopenia syndrome (TTS) after J&J/Janssen COVID-19 vaccination is rare and has occurred in approximately 4 cases per one million doses administered.Allergic Reactions Including Anaphylaxis After Receipt of the First Dose of Pfizer-BioNTech COVID-19 Vaccine - United States, December 14-23, 2020.Allergic Reactions Including Anaphylaxis After Receipt of the First Dose of Moderna COVID-19 Vaccine- United States, December 21, 2020-January 10, 2021.Reports of Anaphylaxis After Receipt of mRNA COVID-19 Vaccines in the US-December 14, 2020-January 18, 2021.Allergic Reactions Including Anaphylaxis After Receipt of the First Dose of Pfizer-BioNTech COVID-19 Vaccine. ![]() Learn more about COVID-19 vaccines and allergic reactions, including anaphylaxis.ĬDC scientists have conducted detailed reviews of cases of anaphylaxis and made the information available to healthcare providers and the public: If it happens, healthcare providers can effectively and immediately treat the reaction. Anaphylaxis, a severe type of allergic reaction, can occur after any kind of vaccination. Anaphylaxis after COVID-19 vaccination is rare and has occurred at a rate of approximately 5 cases per one million vaccine doses administered.CDC is providing timely updates on the following adverse events of interest:
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